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Case Reports
. 2008 Dec;2(4):961-3.
doi: 10.2147/opth.s4022.

Cytomegalovirus retinitis presenting as vasculitis in a patient with Wegener's granulomatosis

Paris G Tranos  1 , Ilias Georgalas, Panagiota Founti, Ioannis Ladas
Affiliations
Case Reports

Cytomegalovirus retinitis presenting as vasculitis in a patient with Wegener's granulomatosis

Paris G Tranos et al. Clin Ophthalmol. 2008 Dec.

Abstract

Purpose: To present an unusual case of cytomegalovirus (CMV) retinitis in a patient with Wegener's granulomatosis.

Results: A 54-year-old lady with Wegener's granulomatosis presented with decreased vision in her left eye. Wegener's retinal vasculitis was diagnosed initially and the patient received treatment with oral steroids. Three days later the patient developed typical CMV retinitis.

Conclusion: The likelihood of CMV retinitis in patients with Wegener's granulomatosis should not be overlooked. Increased awareness in such cases is very important since CMV retinitis may present with less typical manifestations, which makes the correct diagnosis more challenging.

Keywords: Wegener’s granulomatosis; cytomegalovirus retinitis; ganciclovir.

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Figures

Figure 1
Figure 1
Color photograph showing retinitis with scatter retinal hemorrhages in the peripapillary area and along the vascular arcades. Fundal details appear blurred due to coexisting vitritis.
Figure 2
Figure 2
Regression of retinitis following treatment with ganciclovir, leaving retinal pigment epithelial changes and pale optic disc.
See this image and copyright information in PMC

References

    1. Bertelmann E, Liekfeld A, Pleyer U, et al. Cytomegalovirus retinitis in Wegener’s granulomatosis: case report and review of the literature. Acta Ophthalmol Scand. 2005;83:258–61. - PubMed
    1. Haynes BF, Fishman ML, Fauci AS, et al. The ocular manifestations of Wegener’s granulomatosis. Fifteen years experience and review of the literature. Am J Med. 1977;63:131–41. - PubMed
    1. Hoffman GS, Kerr GS, Leavitt RY, et al. Wegener granulomatosis: an analysis of 158 patients. Ann Intern Med. 1992;116:488–98. - PubMed
    1. Nicholson DH. Cytomegalovirus infection of the retina. Int Ophthalmol Clin. 1975;15:151–62. - PubMed
    1. Pertel P, Hirschtick R, Phair J, et al. Risk of developing cytomegalovirus retinitis in persons infected with the human immunodeficiency virus. J Acquir Immune Defic Syndr. 1992;5:1069–74. - PubMed

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