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Case Reports
. 2008 Sep;2(3):657-60.
doi: 10.2147/opth.s2686.

Posterior capsule opacification and neovascularization treated with intravitreal bevacizumab and Nd:YAG capsulotomy

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Free PMC article
Case Reports

Posterior capsule opacification and neovascularization treated with intravitreal bevacizumab and Nd:YAG capsulotomy

Grimelda Yuriana Sánchez-Castro et al. Clin Ophthalmol. 2008 Sep.
Free PMC article

Abstract

We reported a 75-year-old diabetic man, who developed opacification and neovascularization of the posterior capsule after extracapsular cataract extraction and posterior chamber intraocular lens implantation. The patient was treated with two injections of 2.5 mg of intravitreal bevacizumab. The treatment produced an important regression of the posterior capsular new vessels, allowing us to perform a successful Nd:YAG capsulotomy, clearing the visual axis and improving the visualization of the posterior pole. Even though, best corrected visual acuity was 20/200 due to diabetic macular edema.

Keywords: cataract surgery; intravitreal bevacizumab; posterior capsule neovascularization; posterior capsule opacification; postoperative complications.

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Figures

Figure 1
Figure 1
Right slit-lamp images showing PCO with severe neovascularization and granules of pigment over the IOL. A) Direct illumination. B) Retroillumination with mydriasis.
Figure 2
Figure 2
Slit-lamp image immediately after posterior capsulotomy. A small hemorrhage (clot) is seen behind the IOL.
Figure 3
Figure 3
Two months after treatment slit-lamp images. It shows a complete resolution of the clot and a clear visual axis. A) Direct illumination. B) Retroillumination.

References

    1. Avery RL, Pearlman J, Pieramici DJ, et al. Intravitreal bevacizumab (Avastin) in the treatment of proliferative diabetic retinopathy. Ophthalmology. 2006;113:1695–705. - PubMed
    1. Ayata A, Unal M, Erşanli D, et al. Photodynamic therapy for posterior capsule neovascularization. J Cataract Refract Surg. 2007;33:1131–2. - PubMed
    1. Bakri SJ, Snyder MR, Reid JM, et al. Pharmacokinetics of intravitreal bevacizumab (Avastin) Ophthalmology. 2007;114:855–9. - PubMed
    1. Chung J, Kim MY, Kim HS, et al. Effect of cataract surgery on the progression of diabetic retinopathy. J Cataract Refract Surg. 2002;28:626–30. - PubMed
    1. Ebihara Y, Kato S, Oshika T, et al. Posterior capsule opacification after cataract surgery in patients with diabetes mellitus. J Cataract Refract Surg. 2006;32:1184–7. - PubMed

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