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. 2009 Sep;72(9):1663-8.
doi: 10.1021/np9003678.

Oxygenated lignans from the fruits of Schisandra arisanensis

Yuan-Bin Cheng  1 , Meng-Ting Chang, Yi-Wen Lo, Ching-Jen Ho, Yuh-Chi Kuo, Ching-Te Chien, Shun-Ying Chen, Shorong-Shii Liou, Yao-Haur Kuo, Ya-Ching Shen
Affiliations

Oxygenated lignans from the fruits of Schisandra arisanensis

Yuan-Bin Cheng et al. J Nat Prod. 2009 Sep.

Abstract

An acetone extract of the fruits of the Taiwanese medicinal plant Schisandra arisanensis has yielded 11 new oxygenated lignans. Four of these, named arisantetralones A-D (1-4), possess the aryltetralone skeleton, while the other seven, named arisanschinins F-L (5-11), are polyoxygenated C(18)-dibenzocyclooctadiene lignans. Structures were determined on the basis of spectroscopic analyses, especially 2D-NMR techniques. The structure of compound 1 was confirmed by X-ray crystallographic analysis. Immunomodulatory activity of the isolated lignans was tested and evaluated.

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