Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2010 Mar;37(1):60-3.
doi: 10.1016/j.neurad.2009.05.006. Epub 2009 Aug 11.

Interictal arterial spin-labeling MRI perfusion in intractable epilepsy

N Pendse  1 , M Wissmeyer, S Altrichter, M Vargas, J Delavelle, M Viallon, A Federspiel, M Seeck, K Schaller, K O Lövblad
Affiliations

Interictal arterial spin-labeling MRI perfusion in intractable epilepsy

N Pendse et al. J Neuroradiol. 2010 Mar.

Abstract

Introduction: Magnetic resonance imaging (MRI) is required for the investigation of surgically intractable epilepsy. In addition to the standard MRI techniques, perfusion sequences can be added to improve visualization of underlying pathological changes. Arterial spin-labeling (ASL) MRI perfusion does not require contrast administration and, for this reason, may have advantages in these patients.

Methods: We report here on 16 patients with epilepsy who underwent MRI of the brain with ASL and positron emission tomography (PET).

Results: Despite a slightly reduced resolution with ASL, we found a correlation between ASL, PET and electrophysiological data, with hypoperfusion on ASL that corresponded with hypoperfusion on interictal PET.

Conclusion: Given the correlation between ASL and PET and electrophysiology, perfusion with ASL could become part of the standard work-up in patients with epilepsy.

PubMed Disclaimer