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Review
. 2009 Sep;35(5):851-4.
doi: 10.1093/schbul/sbp079. Epub 2009 Aug 12.

Neurexin 1 (NRXN1) deletions in schizophrenia

Affiliations
Review

Neurexin 1 (NRXN1) deletions in schizophrenia

George Kirov et al. Schizophr Bull. 2009 Sep.
No abstract available

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Figures

Fig. 1.
Fig. 1.
Copy Number Variants in NRXN1 in All Studies, Filtered for >100 kb. The shorter form of the gene encodes for the NRXN1β form, while the longer one encodes for the NRXN1α form. Red bars are deletions in cases (n = 8798); blue are those in controls (n = 42 054).

References

    1. Südhof TC. Neuroligins and neurexins link synaptic function to cognitive disease. Nature. 2008;455:903–911. - PMC - PubMed
    1. Ullrich B, Ushkaryov YA, Südhof TC. Cartography of neurexins: more than 1000 isoforms generated by alternative splicing and expressed in distinct subsets of neurons. Neuron. 1995;14:497–507. - PubMed
    1. Kumar RA, Christian SL. Genetics of autism spectrum disorders. Curr Neurol Neurosci Rep. 2009;9:188–197. review. - PubMed
    1. Feng J, Schroer R, Yan J, et al. High frequency of neurexin 1beta signal peptide structural variants in patients with autism. Neurosci Lett. 2006;409:10–13. - PubMed
    1. Autism Genome Project Consortium. Mapping autism risk loci using genetic linkage and chromosomal rearrangements. Nat Genet. 2007;39:319–328. - PMC - PubMed

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