Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2009 Oct;47(10):3138-41.
doi: 10.1128/JCM.01070-09. Epub 2009 Aug 12.

Molecular identification of Aspergillus species collected for the Transplant-Associated Infection Surveillance Network

S Arunmozhi Balajee  1 , Rui Kano, John W Baddley, Stephen A Moser, Kieren A Marr, Barbara D Alexander, David Andes, Dimitrios P Kontoyiannis, Giancarlo Perrone, Stephen Peterson, Mary E Brandt, Peter G Pappas, Tom Chiller
Affiliations

Molecular identification of Aspergillus species collected for the Transplant-Associated Infection Surveillance Network

S Arunmozhi Balajee et al. J Clin Microbiol. 2009 Oct.

Abstract

A large aggregate collection of clinical isolates of aspergilli (n = 218) from transplant patients with proven or probable invasive aspergillosis was available from the Transplant-Associated Infection Surveillance Network, a 6-year prospective surveillance study. To determine the Aspergillus species distribution in this collection, isolates were subjected to comparative sequence analyses by use of the internal transcribed spacer and beta-tubulin regions. Aspergillus fumigatus was the predominant species recovered, followed by A. flavus and A. niger. Several newly described species were identified, including A. lentulus and A. calidoustus; both species had high in vitro MICs to multiple antifungal drugs. Aspergillus tubingensis, a member of the A. niger species complex, is described from clinical specimens; all A. tubingensis isolates had low in vitro MICs to antifungal drugs.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Alcazar-Fuoli, L., E. Mellado, A. Alastruey-Izquierdo, M. Cuenca-Estrella, and J. L. Rodriguez-Tudela. 2008. Aspergillus section Fumigati: antifungal susceptibility patterns and sequence-based identification. Antimicrob. Agents Chemother. 52:1244-1251. - PMC - PubMed
    1. Alhambra, A., M. Catalan, M. D. Moragues, S. Brena, J. Ponton, J. C. Montejo, and A. Del Palacio. 2008. Isolation of Aspergillus lentulus in Spain from a critically ill patient with chronic obstructive pulmonary disease. Rev. Iberoam. Micol. 25:246-249. - PubMed
    1. Ascioglu, S., J. H. Rex, B. de Pauw, J. E. Bennett, J. Bille, F. Crokaert, D. W. Denning, J. P. Donnelly, J. E. Edwards, Z. Erjavec, D. Fiere, O. Lortholary, J. Maertens, J. F. Meis, T. F. Patterson, J. Ritter, D. Selleslag, P. M. Shah, D. A. Stevens, and T. J. Walsh. 2002. Defining opportunistic invasive fungal infections in immunocompromised patients with cancer and hematopoietic stem cell transplants: an international consensus. Clin. Infect. Dis. 34:7-14. - PubMed
    1. Balajee, S. A., J. L. Gribskov, E. Hanley, D. Nickle, and K. A. Marr. 2005. Aspergillus lentulus sp. nov., a new sibling species of A. fumigatus. Eukaryot. Cell 4:625-632. - PMC - PubMed
    1. Balajee, S. A., J. Houbraken, P. E. Verweij, S. B. Hong, T. Yaghuchi, J. Varga, and R. A. Samson. 2007. Aspergillus species identification in the clinical setting. Studies Mycol. 59:39-46. - PMC - PubMed

Publication types

MeSH terms