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. 2009 Oct;47(10):3138-41.
doi: 10.1128/JCM.01070-09. Epub 2009 Aug 12.

Molecular identification of Aspergillus species collected for the Transplant-Associated Infection Surveillance Network

S Arunmozhi Balajee  1 , Rui Kano, John W Baddley, Stephen A Moser, Kieren A Marr, Barbara D Alexander, David Andes, Dimitrios P Kontoyiannis, Giancarlo Perrone, Stephen Peterson, Mary E Brandt, Peter G Pappas, Tom Chiller
Affiliations

Molecular identification of Aspergillus species collected for the Transplant-Associated Infection Surveillance Network

S Arunmozhi Balajee et al. J Clin Microbiol. 2009 Oct.

Abstract

A large aggregate collection of clinical isolates of aspergilli (n = 218) from transplant patients with proven or probable invasive aspergillosis was available from the Transplant-Associated Infection Surveillance Network, a 6-year prospective surveillance study. To determine the Aspergillus species distribution in this collection, isolates were subjected to comparative sequence analyses by use of the internal transcribed spacer and beta-tubulin regions. Aspergillus fumigatus was the predominant species recovered, followed by A. flavus and A. niger. Several newly described species were identified, including A. lentulus and A. calidoustus; both species had high in vitro MICs to multiple antifungal drugs. Aspergillus tubingensis, a member of the A. niger species complex, is described from clinical specimens; all A. tubingensis isolates had low in vitro MICs to antifungal drugs.

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References

    1. Alcazar-Fuoli, L., E. Mellado, A. Alastruey-Izquierdo, M. Cuenca-Estrella, and J. L. Rodriguez-Tudela. 2008. Aspergillus section Fumigati: antifungal susceptibility patterns and sequence-based identification. Antimicrob. Agents Chemother. 52:1244-1251. - PMC - PubMed
    1. Alhambra, A., M. Catalan, M. D. Moragues, S. Brena, J. Ponton, J. C. Montejo, and A. Del Palacio. 2008. Isolation of Aspergillus lentulus in Spain from a critically ill patient with chronic obstructive pulmonary disease. Rev. Iberoam. Micol. 25:246-249. - PubMed
    1. Ascioglu, S., J. H. Rex, B. de Pauw, J. E. Bennett, J. Bille, F. Crokaert, D. W. Denning, J. P. Donnelly, J. E. Edwards, Z. Erjavec, D. Fiere, O. Lortholary, J. Maertens, J. F. Meis, T. F. Patterson, J. Ritter, D. Selleslag, P. M. Shah, D. A. Stevens, and T. J. Walsh. 2002. Defining opportunistic invasive fungal infections in immunocompromised patients with cancer and hematopoietic stem cell transplants: an international consensus. Clin. Infect. Dis. 34:7-14. - PubMed
    1. Balajee, S. A., J. L. Gribskov, E. Hanley, D. Nickle, and K. A. Marr. 2005. Aspergillus lentulus sp. nov., a new sibling species of A. fumigatus. Eukaryot. Cell 4:625-632. - PMC - PubMed
    1. Balajee, S. A., J. Houbraken, P. E. Verweij, S. B. Hong, T. Yaghuchi, J. Varga, and R. A. Samson. 2007. Aspergillus species identification in the clinical setting. Studies Mycol. 59:39-46. - PMC - PubMed

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