Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Multicenter Study
. 2009 Oct;16(10):1527-8.
doi: 10.1128/CVI.00183-09. Epub 2009 Aug 12.

Kinetic patterns of Candida albicans germ tube antibody in critically ill patients: influence on mortality

Rafael Zaragoza  1 , Javier Pemán, Guillermo Quindós, Jose R Iruretagoyena, María S Cuétara, Paula Ramírez, Maria D Gómez, Juan J Camarena, Angel Viudes, José Pontón; Candida Albicans Germ Tube Antibody Detection in Critically Ill Patients Study Group
Collaborators, Affiliations
Multicenter Study

Kinetic patterns of Candida albicans germ tube antibody in critically ill patients: influence on mortality

Rafael Zaragoza et al. Clin Vaccine Immunol. 2009 Oct.

Abstract

The influence of kinetic patterns of Candida albicans germ tube antibodies (CAGTA) on mortality was analyzed in six intensive care units. Statistically significant lower mortality rates were found in patients with patterns of increasing CAGTA titers who had been treated with antifungal agents. Thus, antifungal treatment should be considered when CAGTA titers are increasing in critically ill patients.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

References

    1. Bromuro, C., V. R. La, S. Sandini, F. Urbani, C. M. Ausiello, L. Morelli, C. Fé d'ostiani, L. Romani, and A. Cassone. 1998. A 70-kilodalton recombinant heat shock protein of Candida albicans is highly immunogenic and enhances systemic murine candidiasis. Infect. Immun. 66:2154-2162. - PMC - PubMed
    1. Garey, K. W., M. Rege, M. P. Pai, D. E. Mingo, K. J. Suda, R. S. Turpin, and D. T. Bearden. 2006. Time to initiation of fluconazole therapy impacts mortality in patients with candidemia: a multi-institutional study. Clin. Infect. Dis. 43:25-31. - PubMed
    1. Gibot, S. 2005. Clinical review: role of triggering receptor expressed on myeloid cells-1 during sepsis. Crit. Care 9:485-489. - PMC - PubMed
    1. Iruretagoyena, J. R., P. Regulez, G. Quindós, and J. Pontón. 2000. Antibodies to Candida albicans germ tubes in two intensive care patients with invasive candidiasis. Rev. Iberoam. Micol. 17:93-96. - PubMed
    1. Montagnoli, C., S. Sandini, A. Bacci, L. Romani, and R. La Valle. 2004. Immunogenicity and protective effect of recombinant enolase of Candida albicans in a murine model of systemic candidiasis. Med. Mycol. 42:319-324. - PubMed

Publication types