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. 2009 Sep 7;7(17):3382-4.
doi: 10.1039/b909701e. Epub 2009 Jul 9.

Palladium-catalysed synthesis of 1-isoindolecarboxylic acid esters and sequential Diels-Alder reactions: access to bridged- and fused-ring heterocycles

Daniel Solé  1 , Olga Serrano
Affiliations

Palladium-catalysed synthesis of 1-isoindolecarboxylic acid esters and sequential Diels-Alder reactions: access to bridged- and fused-ring heterocycles

Daniel Solé et al. Org Biomol Chem. .

Abstract

The Pd-catalysed intramolecular alpha-arylation of alpha-amino acid esters provides a useful methodology for the synthesis of substituted isoindole derivatives, which have been used in Diels-Alder reactions to access diverse skeletal frameworks.

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