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Comment
. 2009 Aug 12;17(8):1035-6.
doi: 10.1016/j.str.2009.07.003.

How do adhesion proteins stick?

Keith Weninger
Free article
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How do adhesion proteins stick?

Keith Weninger. Structure. .
Free article

Abstract

Cadherin homodimerization mediates cell-cell adhesion, but one stabilizing structural element has inspired questions about assembly mechanisms. Combining single molecule fluorescence and force analyses allowed Sivasankar et al. to provide strong evidence for an induced fit pathway to dimerization.

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