[Vaginal adenosis and vaginal intraepithelial neoplasia: a review of the literature and a case report]

Abstract

Vaginal adenosis is an uncommon pathology, characterized by the presence of cylindrical epithelium in the vagina. This pathology is considered rare if not found in women exposed in utero to diethylstilbestrol (dietilestilbestrol). Vaginal intraepithelial neoplasia (VAIN) is another uncommon condition in women who have not been hysterectomized to treat cervical intraepithelial neoplasia (CIN), with an incidence of 0.3 per 100,000 women. On the other hand 0.9% of the patients who have been poshysterectomized to treat CIN develop VAIN. This paper aims at reviewing the literature on vaginal adenosis, vaginal intraepithelial neoplasia and their possible treatments. In addition, the paper reports on a case of vaginal adenosis in a young female patient with concomitant VAIN 2, the CO2 laser ablation performed, and the short-term results obtained.