doi: 10.1016/0140-6736(90)90667-t.
Rapid detection of herpes-simplex-virus DNA in cerebrospinal fluid of patients with herpes simplex encephalitis
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- PMID: 1968171
- DOI: 10.1016/0140-6736(90)90667-t
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Rapid detection of herpes-simplex-virus DNA in cerebrospinal fluid of patients with herpes simplex encephalitis
Lancet.
.
Abstract
Herpes-simplex-virus (HSV) DNA in cerebrospinal fluid was amplified by use of the polymerase chain reaction and identified by hybridisation to a specific oligonucleotide probe. Specimens of cerebrospinal fluid (CSF) from 4 of 4 patients with herpes simplex encephalitis were positive for HSV DNA, whereas CSF specimens from 6 patients with other central-nervous-system infections were negative. This technique may expedite diagnosis of herpes simplex encephalitis.
Comment in
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Obstacle to early diagnosis of herpes simplex encephalitis via CSF.Lancet. 1990 Jul 14;336(8707):113. doi: 10.1016/0140-6736(90)91626-l. Lancet. 1990. PMID: 1975295 No abstract available.
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