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. 2009 Dec;70(6):455-61.
doi: 10.1016/j.ando.2009.07.001. Epub 2009 Aug 15.

[Update of oral vitamin B12]

[Article in French]
E Andres  1 , K Serraj, M Mecili, E Ciobanu, T Vogel, T Weitten
Affiliations

[Update of oral vitamin B12]

[Article in French]
E Andres et al. Ann Endocrinol (Paris). 2009 Dec.

Abstract

Objective: The objective of this review is to evaluate the usefulness of oral cobalamin (vitamin B12) treatment.

Material and method: PubMed was systematically searched for English and French articles published from January 1990 to January 2007.

Results: Prospective randomized studies (n = 3), a systematic review by the Cochrane group (n = 1) and prospective studies in well-determined population (n = 5) provide evidence that oral cyanocobalamin therapy may adequately treat cobalamin deficiency in elderly patients. However, the current literature may not suggest a strategy in terms of the form (hydroxy- or cyanocobalamin), frequency and duration of the treatment.

Conclusion: This present review confirms the previously reported efficacy of oral cyanocobalamin treatment in elderly patients.

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