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. 2009 Oct 15;25(20):2734-6.
doi: 10.1093/bioinformatics/btp489. Epub 2009 Aug 14.

YADA: a tool for taking the most out of high-resolution spectra

Paulo C Carvalho  1 , Tao Xu, Xuemei Han, Daniel Cociorva, Valmir C Barbosa, John R Yates 3rd
Affiliations

YADA: a tool for taking the most out of high-resolution spectra

Paulo C Carvalho et al. Bioinformatics. .

Abstract

YADA can deisotope and decharge high-resolution mass spectra from large peptide molecules, link the precursor monoisotopic peak information to the corresponding tandem mass spectrum, and account for different co-fragmenting ion species (multiplexed spectra). We describe how YADA enables a pipeline consisting of ProLuCID and DTASelect for analyzing large-scale middle-down proteomics data.

Availability: http://fields.scripps.edu/yada

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Figures

Fig. 1.
Fig. 1.
The key steps of the proposed pipeline for middle-down proteomic analysis.
See this image and copyright information in PMC

References

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