Atlasin GTPases shape up ER networks
- PMID: 19686675
- DOI: 10.1016/j.devcel.2009.07.019
Atlasin GTPases shape up ER networks
Abstract
The endoplasmic reticulum (ER) adopts a remarkable array of flattened membrane structures and branched tubular networks to support cellular function. Recent studies reveal that the integral membrane atlastin GTPases, which are linked to neurodegenerative diseases, catalyze membrane fusion and are required for the formation of branched membrane networks characteristic of the ER.
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