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. 2010 Jun;33(3):469-74.
doi: 10.1007/s00270-009-9687-3. Epub 2009 Aug 18.

Always contact a vascular interventional specialist before amputating a patient with critical limb ischemia

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Always contact a vascular interventional specialist before amputating a patient with critical limb ischemia

Rosemarie Met et al. Cardiovasc Intervent Radiol. 2010 Jun.

Abstract

Patients with severe critical limb ischemia (CLI) due to long tibial artery occlusions are often poor candidates for surgical revascularization and frequently end up with a lower limb amputation. Subintimal angioplasty (SA) offers a minimally invasive alternative for limb salvage in this severely compromised patient population. The objective of this study was to evaluate the results of SA in patients with CLI caused by long tibial occlusions who have no surgical options for revascularization and are facing amputation. We retrospectively reviewed all consecutive patients with CLI due to long tibial occlusions who were scheduled for amputation because they had no surgical options for revascularization and who were treated by SA. A total of 26 procedures in 25 patients (14 males; mean age, 70 +/- 15 [SD] years) were evaluated. Technical success rate was 88% (23/26). There were four complications, which were treated conservatively. Finally, in 10 of 26 limbs, no amputation was needed. A major amputation was needed in 10 limbs (7 below-knee amputations and 3 above-knee amputations). Half of the major amputations took place within 3 months after the procedure. Cumulative freedom of major amputation after 12 months was 59% (SE = 11%). In six limbs, amputation was limited to a minor amputation. Seven patients (28%) died during follow-up. In conclusion, SA of the tibial arteries seem to be a valuable treatment option to prevent major amputation in patients with CLI who are facing amputation due to lack of surgical options.

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Figures

Fig. 1
Fig. 1
Angiogram of the lower leg and foot of a patient before (A, B) and after (C, D) subintimal angioplasty of the popliteal and anterior tibial artery
Fig. 2
Fig. 2
Clinical outcome
Fig. 3
Fig. 3
Kaplan–Meier limb salvage (A; 26 limbs) and survival (B; 25 patients) curves. SE standard error

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References

    1. Norgren L, Hiatt WR, Dormandy JA, et al. Inter-society consensus for the management of peripheral arterial disease (TASC II) Eur J Vasc Endovasc Surg. 2007;33(Suppl 1):S1–S75. doi: 10.1016/j.ejvs.2006.09.024. - DOI - PubMed
    1. Adam DJ, Beard JD, Cleveland T, et al. Bypass versus angioplasty in severe ischaemia of the leg (BASIL): multicentre, randomised controlled trial. Lancet. 2005;366(9501):1925–1934. doi: 10.1016/S0140-6736(05)67704-5. - DOI - PubMed
    1. Bertelè V, Roncaglioni MC, Pangrazzi J, et al. Clinical outcome and its predictors in 1560 patients with critical leg ischaemia. Chronic Critical Leg Ischaemia Group. Eur J Vasc Endovasc Surg. 1999;18(5):401–410. doi: 10.1053/ejvs.1999.0934. - DOI - PubMed
    1. Marston WA, Davies SW, Armstrong B, et al. Natural history of limbs with arterial insufficiency and chronic ulceration treated without revascularization. J Vasc Surg. 2006;44(1):108–114. doi: 10.1016/j.jvs.2006.03.026. - DOI - PubMed
    1. Ingle H, Nasim A, Bolia A, et al. Subintimal angioplasty of isolated infragenicular vessels in lower limb ischemia: long-term results. J Endovasc Ther. 2002;9(4):411–416. doi: 10.1583/1545-1550(2002)009<0411:SAOIIV>2.0.CO;2. - DOI - PubMed

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