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Comparative Study
. 1990 Feb;53(2):102-5.
doi: 10.1136/jnnp.53.2.102.

Nasogastric and intravenous infusions of (+)-4-propyl-9-hydroxynaphthoxazine (PHNO) in Parkinson's disease

R J Coleman  1 , N P Quinn, M Traub, C D Marsden
Affiliations
Comparative Study

Nasogastric and intravenous infusions of (+)-4-propyl-9-hydroxynaphthoxazine (PHNO) in Parkinson's disease

R J Coleman et al. J Neurol Neurosurg Psychiatry. 1990 Feb.

Abstract

(+)-4-propyl-9-hydroxynaphthoxazine (PHNO) is a new dopamine agonist which is capable of producing a sustained response in parkinsonian patients with "on-off" fluctuations when given as a continuous infusion either nasogastrically or intravenously. These data suggest that a sustained release formulation of PHNO may provide a significant, new treatment for patients with "on-off" fluctuations.

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