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Case Reports
. 2009 Jun;19(3):262-8.
doi: 10.1111/j.1476-4431.2009.00407.x.

Critical illness-related corticosteroid insufficiency in a dog with septic shock

Jamie L Peyton  1 , Jamie M Burkitt
Affiliations
Case Reports

Critical illness-related corticosteroid insufficiency in a dog with septic shock

Jamie L Peyton et al. J Vet Emerg Crit Care (San Antonio). 2009 Jun.

Abstract

Objective: To describe a case of hydrocortisone-responsive hypotension and critical illness-related corticosteroid insufficiency (CIRCI) in a dog with septic shock.

Case summary: A dog with aspiration pneumonia developed septic shock with pressor-refractory hypotension. A standard ACTH stimulation test was performed that showed a blunted cortisol response consistent with CIRCI. Reversal of shock was achieved within 2 hours of hydrocortisone administration, and complete weaning from pressors was accomplished over the subsequent 8 hours. The patient recovered and was discharged from the hospital. An ACTH stimulation test performed 1 month after hospital discharge showed normal adrenal responsiveness consistent with resolution of CIRCI.

New or unique information provided: This case is the first published report of hydrocortisone-responsive hypotension and transient CIRCI associated with naturally occurring septic shock in a dog.

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