[Application of Mentype Argus X-8 kit in forensic paternity testing]

Abstract

Objective: To evaluate the application value of Mentype Argus X-8 kit in Chinese population, and to gather the genetic data of the eight X-STR loci.

Methods: The X-STR of 177 blood samples of unrelated East China Han population and 104 duo paternity testing cases was typed using Mentype Argus X-8 kit. The allele frequency and genetic data of the eight loci were investigated.

Results: The PIC of the eight X-STR loci was between 0.4454 and 0.9187. Among them, DXS10135 and DXS10101 had the highest PIC and exclusion rate in paternity cases. The other seven loci showed no difference in sex-related allele frequency except DXS7132. In addition, there were several new alleles detected including DXS10074 (allele 15.3), DXS10101 (allele 36) and DXS10134 (allele 37.3).

Conclusion: Eight X-STR loci included in Mentype Argus X-8 kit are high polymorphic and valuable.