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Review
. 2009 Dec 15;185(1):1-14.
doi: 10.1016/j.jneumeth.2009.08.013. Epub 2009 Aug 20.

Viral vector approaches to modify gene expression in the brain

Alessandro Papale  1 , Milica Cerovic, Riccardo Brambilla
Affiliations
Review

Viral vector approaches to modify gene expression in the brain

Alessandro Papale et al. J Neurosci Methods. .

Abstract

The use of viral vectors as gene transfer tools for the central nervous system has seen a significant growth in the last decade. Improvements in the safety, efficiency and specificity of vectors for clinical applications have proven to be beneficial also for basic neuroscience research. This review will discuss the viral systems currently available to neuroscientists and some of the recent achievements in the study of synaptic function, memory and drug addiction.

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