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Comment
. 2009 Sep 1;15(17):5291-3.
doi: 10.1158/1078-0432.CCR-09-1444. Epub 2009 Aug 25.

Complexity made simple in diffuse large B-cell lymphoma

Jon Aster  1 , Jeffery Kutok
Affiliations
Comment

Complexity made simple in diffuse large B-cell lymphoma

Jon Aster et al. Clin Cancer Res. .

Abstract

Diffuse large B cell lymphoma (DLBCL) is a heterogeneous disease and response to therapy is difficult to predict. An algorithm to sort DLBCL cases using a series of five immunohistochemical markers (GCET1, CD10, BCL6, MUM1, FOXP1) accurately predicts survival in patients treated with current chemotherapeutic regimens.

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Figures

Figure 1
Figure 1
Variable immunohistochemical staining for BCL6 in four diffuse large B cell lymphomas (A–D; original magnification 400x).
See this image and copyright information in PMC

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