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. 2009 Apr 21;3(8):340-3.
doi: 10.6026/97320630003340.

Specific gene hypomethylation and cancer: new insights into coding region feature trends

Elias Daura-Oller  1 , Maria Cabre, Miguel A Montero, Jose L Paternain, Antoni Romeu
Affiliations

Specific gene hypomethylation and cancer: new insights into coding region feature trends

Elias Daura-Oller et al. Bioinformation. .

Abstract

Giving coding region structural features a role in the hypomethylation of specific genes, the occurrence of G+C content, CpG islands, repeat and retrotransposable elements in demethylated genes related to cancer has been evaluated. A comparative analysis among different cancer types has also been performed. In this work, the inter-cancer coding region features comparative analysis carried out, show insights into what structural trends/patterns are present in the studied cancers.

Keywords: CpG islands; cancer; epigenetics; hypomethylation.

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Figures

Figure 1
Figure 1
Boxplot graphs (median and interquartile) with the comparison of the different [bp] % seuence characteristic distributions across the different cancer types*. Note that the different average numbers are connected by a drawing line.
See this image and copyright information in PMC

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