doi: 10.6026/97320630003340.
Specific gene hypomethylation and cancer: new insights into coding region feature trends
Affiliations
- PMID: 19707296
- PMCID: PMC2720671
- DOI: 10.6026/97320630003340
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Specific gene hypomethylation and cancer: new insights into coding region feature trends
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Abstract
Giving coding region structural features a role in the hypomethylation of specific genes, the occurrence of G+C content, CpG islands, repeat and retrotransposable elements in demethylated genes related to cancer has been evaluated. A comparative analysis among different cancer types has also been performed. In this work, the inter-cancer coding region features comparative analysis carried out, show insights into what structural trends/patterns are present in the studied cancers.
Keywords: CpG islands; cancer; epigenetics; hypomethylation.
Figures
Boxplot graphs (median and interquartile) with the comparison of the different [bp] % seuence characteristic
distributions across the different cancer types*. Note that the different average numbers are connected by a drawing line.
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