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Review
. 2009 Jul;31(2):145-9.
doi: 10.1007/s00281-009-0174-3. Epub 2009 Aug 26.

The mucosal firewalls against commensal intestinal microbes

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Free article
Review

The mucosal firewalls against commensal intestinal microbes

Andrew J Macpherson et al. Semin Immunopathol. 2009 Jul.
Free article

Abstract

Mammals coexist with an extremely dense microbiota in the lower intestine. Despite the constant challenge of small numbers of microbes penetrating the intestinal surface epithelium, it is very unusual for these organisms to cause disease. In this review article, we present the different mucosal firewalls that contain and allow mutualism with the intestinal microbiota.

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