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. 2010 May;35(4):394-404.
doi: 10.1093/jpepsy/jsp074. Epub 2009 Aug 26.

Adherence to pediatric asthma treatment in economically disadvantaged African-American children and adolescents: an application of growth curve analysis

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Adherence to pediatric asthma treatment in economically disadvantaged African-American children and adolescents: an application of growth curve analysis

Jennifer Rohan et al. J Pediatr Psychol. 2010 May.

Abstract

Objectives: The primary aims of the study were to: (a) describe the trajectories of adherence to daily inhaled corticosteroid (ICS) medication for a year in economically disadvantaged, African-American youth with asthma based on growth curve modeling; and (b) test the relationship of treatment adherence to symptom control, quick-relief medication, and healthcare utilization.

Methods: This prospective study measured adherence to daily ICS treatment using electronic monitoring in 92 children and adolescents with moderate to severe asthma for 9-12 months and assessed clinical outcomes, including asthma-related symptoms, quick-relief medication, and healthcare utilization.

Results: Youth showed a decrement in treatment adherence to less than half of prescribed corticosteroid treatment over the course of the study, which related to increased healthcare utilization (p < .04), but not to asthma symptoms or albuterol use.

Conclusion: Economically disadvantaged youth with asthma demonstrate high rates of chronic nonadherence that warrant identification and intervention to reduce asthma-related healthcare utilization.

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Figures

Figure 1.
Figure 1.
Individual growth curve for fluticasone use.
Figure 2.
Figure 2.
Conditional growth curve for utilization and adherence.

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