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Comment
. 2009 Aug 28;16(8):798-800.
doi: 10.1016/j.chembiol.2009.08.003.

Putative fat fighter hits the middle man

James Robert Krycer  1 , Andrew John Brown
Affiliations
Comment

Putative fat fighter hits the middle man

James Robert Krycer et al. Chem Biol. .

Abstract

In this issue, Kamisuki and colleagues characterize fatostatin. This compound inhibits the activity of SREBPs, the master transcription factors of lipid homeostasis. This useful laboratory tool also improved the lipid profile of obese mice; does this have clinical implications?

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