Thymosin-induced human serum factor increasing cyclic AMP
- PMID: 197166
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Thymosin-induced human serum factor increasing cyclic AMP
J Immunol.
1977 Sep.
Abstract
Thymosin has virtually no in vitro effect on cyclic AMP levels in thymocytes and seems not to react with either the beta-adrenergic receptor or with the putative human serum thymic factor (SF) receptor. However, when thymosin is injected into patients lacking SF activity, it induces the appearance of a serum factor which increases cellular cyclic AMP levels in thymocytes in vitro. This factor appears to act on a membrane site distinct from the beta-adrenergic receptors.
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