Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1977 Oct 1;146(4):1088-95.
doi: 10.1084/jem.146.4.1088.

Genetic control of radiation leukemia virus-induced tumorigenesis II. Influence of Srlv-1, a locus not linked to H-2

D Meruelo, M Lieberman, B Deak, H O McDevitt

Genetic control of radiation leukemia virus-induced tumorigenesis II. Influence of Srlv-1, a locus not linked to H-2

D Meruelo et al. J Exp Med. .

Abstract

A single locus, tentatively denoted Srlv-1 (susceptibility to radiation leukemia virus [RadLV]-1), confers dominant susceptibility to RadLV-induced leukemogenesis. Srlv-1 is not linked to H-2, and appears to be distinct from Fv-1 and Fv-2. Preliminary data suggest that Srlv-1 affected virus proliferation. A striking feature of this system is that Srlv-1 overrides the protection afforded by the H2D-associated dominant resistance to RadLV-induced neoplasia.

PubMed Disclaimer

References

    1. J Exp Med. 1957 Apr 1;105(4):307-18 - PubMed
    1. Science. 1959 Aug 14;130(3372):387-8 - PubMed
    1. Nature. 1964 Jul 25;203:420-2 - PubMed
    1. Virology. 1964 Nov;24:513-8 - PubMed
    1. J Exp Med. 1977 Oct 1;146(4):1079-87 - PubMed

Publication types

Substances