[Incidence of impaired glucose tolerance in hospitalized essential hypertension patients without diabetes mellitus history and with normal fasting glucose]

Abstract

Objective: To observe the incidence of impaired glucose tolerance in hospitalized patients with essential hypertension without diabetes mellitus history and with normal fasting glucose.

Methods: A total of 586 hospitalized patients with essential hypertension and without known diabetes mellitus (DM) and with normal fasting blood glucose (FBG < 5.6 mmol/L) were included in this epidemiologic cross-sectional survey and screening study and received oral glucose tolerance test (OGTT). Associations between postprandial blood sugar and age, gender, body mass index, blood pressure level, blood lipid level, carotid arterial sclerosis were analyzed.

Results: (1) Among 586 patients, the number of impaired glucose tolerance (IGT) was 159, the number of newly diagnosed DM was 41 and the prevalence rates of newly diagnosed DM and impaired glucose tolerance (IGT) were 7.0% and 27.1% respectively. (2) Incidence of carotid arterial sclerosis was 67.5% in patients with impaired glucose tolerance and 59.6% in patients with normal glucose tolerance (P > 0.05).

Conclusion: Our results showed that incidence of newly diagnosed disturbed glucometabolic status is common among patients with essential hypertension without DM history and normal FBG. OGTT should be used as a routine procedure in these patients for the purpose of early intervention in hypertensive patients with abnormal glucometabolic status.