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. 2009 Sep;10(9):941-5.
doi: 10.1038/embor.2009.193.

The case for open-access chemical biology. A strategy for pre-competitive medicinal chemistry to promote drug discovery

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The case for open-access chemical biology. A strategy for pre-competitive medicinal chemistry to promote drug discovery

Johan Weigelt. EMBO Rep. 2009 Sep.
No abstract available

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Conflict of interest statement

The author declares no conflict of interest beyond his affiliation to the Structural Genomics Consortium as noted below.

Figures

Figure 1
Figure 1
Three models of the interaction between pharmaceutical companies and academia. (A) The traditional model comprises a closed collaboration between a company and an academic researcher. (B) The closed consortium model in which several parties contribute to a joint project. Results and/or intellectual property rights are normally retained by consortium members. (C) The open consortium model in the form of a public–private partnership. A joint project, governed by its funders, is carried out at a host institution or as a separate legal entity. Results are made freely available to allow research in the public domain.
Figure 2
Figure 2
Model of the open-access chemical biology consortium. The public–private partnership (PPP) is mandated to create chemical probes that target proteins involved in epigenetic signalling. Results—tools and data—are shared freely to facilitate further exploration and new discoveries. The increased knowledge will allow commercial projects at a later stage with an increased chance of success. The model can also be viewed as a general scheme for pre-competitive public–private collaboration. The Structural Genomics Consortium was originally created as a structural genomics PPP following the same principles.
None

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