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Case Reports
. 2009:2009:148795.
doi: 10.1155/2009/148795. Epub 2009 Aug 4.

Cronkhite-Canada Syndrome: Gastric Involvement Diagnosed by MDCT

Affiliations
Case Reports

Cronkhite-Canada Syndrome: Gastric Involvement Diagnosed by MDCT

Jonathan D Samet et al. Case Rep Med. 2009.

Abstract

Chronkhite-Canada is a rare nonfamilial polyposis syndrome that usually presents as chronic malabsorption in adults. We present a case of a-73-year old woman with chronic gastrointestinal bleeding and malnutrition. On CT imaging she was found to have massive gastric polyps, which on biopsy was most consistent with Cronkhite-Canada syndrome.

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Figures

Figure 1
Figure 1
(a) Axial CT through the gastric cardia demonstrates large lobular folds forming a mass-like configuration. (b) Axial CT through the gastric body shows a distended stomach with multiple lobular mass-like folds.
Figure 2
Figure 2
(a) Image obtained during upper endoscopy of the stomach demonstrates multiple polyps and edematous mucosa. (b) Image obtained during upper endoscopy of the stomach demonstrates numerous polyps which coalesce, giving a mass-like appearance.
Figure 3
Figure 3
Histopathology of gastric mucosa. (a) Gastric polyp with hyperplastic features of foveolar epithelium (curved arrows) in a background of prominent lamina propria edema and inflammation (straight arrow). (b) Nonpolypoid gastric mucosa. Similar features are present; hyperplastic epithelium (curved arrows) and lamina propria edema (straight arrow) as in Panel (a).

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