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Case Reports
. 1990 Mar;36(3):266-9.

[Severe antihistamine poisoning complicated by ventricular tachycardia]

[Article in Czech]
J Bastecký  1 , J Kvasnicka, J Vortel, M Tauchman, V Wasylivová
Affiliations
  • PMID: 1972306
Case Reports

[Severe antihistamine poisoning complicated by ventricular tachycardia]

[Article in Czech]
J Bastecký et al. Vnitr Lek. 1990 Mar.

Abstract

A 26-year-old female clerk without previous heart disease ingested with suicidal intensions antihistaminic drugs--H1 blockers, astemizole (a total of 700 mg) and terfenadine (a total of 900-1200 mg). The main sign of intoxication was repeated polymorphous ventricular tachycardia type torsade de pointes, which at the onset of hospitalization changed into ventricular fibrillation. Therapeutically the impaired rhythm was controlled by electric cardioversion and atrial stimulation with a frequency of 120/min. On the third day it was possible to discontinue atrial stimulation and later the patient was discharged without any permanent sequelae.

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