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Review
. 2009;10(9):237.
doi: 10.1186/gb-2009-10-9-237. Epub 2009 Sep 2.

The promise and reality of personal genomics

Bryndis Yngvadottir  1 , Daniel G Macarthur, Hanjun Jin, Chris Tyler-Smith
Affiliations
Review

The promise and reality of personal genomics

Bryndis Yngvadottir et al. Genome Biol. 2009.

Abstract

The publication of the highest-quality and best-annotated personal genome yet tells us much about sequencing technology, something about genetic ancestry, but still little of medical relevance.

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Figures

Figure 1
Figure 1
Ancestry inferences from personal genomes in a worldwide context. The program STRUCTURE was used to assign six personal genomes (Table 1) and individuals from the HGDP-CEPH and HapMap panels to seven clusters on the basis of their genotypes as described previously [9]. Upper section: each thin vertical bar represents an individual and is divided into colors corresponding to their inferred ancestry from the seven genetic clusters. Individuals are ordered according to their name or code (personal genomes) or population of origin (HGDP-CEPH and HapMap). Personal genomes fall predominantly into the green (NA18507; African), cyan (Venter, Watson; European) or orange (YH, SJK, AK1; East Asian) clusters. Lower section: expanded view of the personal genome inferred ancestries.
See this image and copyright information in PMC

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