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Review

. 2009 Aug;9(4):371-5.

doi: 10.7861/clinmedicine.9-4-371.

Pemphigus: a brief review

Richard W Groves¹

Affiliations

PMID: 19728517
PMCID: PMC4952511
DOI: 10.7861/clinmedicine.9-4-371

Review

Pemphigus: a brief review

Richard W Groves. Clin Med (Lond). 2009 Aug.

. 2009 Aug;9(4):371-5.

doi: 10.7861/clinmedicine.9-4-371.

Author

Richard W Groves¹

Affiliation

¹ Immunodermatology Unit, St. John's Institute of Dermatology Guy's Hospital, London. richard.groves@kcl.ac.uk

PMID: 19728517
PMCID: PMC4952511
DOI: 10.7861/clinmedicine.9-4-371

No abstract available

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Figures

Fig 1. — Fig 1.
Histopathology of pemphigus vulgaris. There is rounding up and separation of keratinocytes from each other, resulting in intra-epithelial blister formation.

Fig 2. — Fig 2.
Pemphigus vulgaris direct immunofluorescence shows deposition of IgG in the intercellular spaces between epidermal keratinocytes.

Fig 3. — Fig 3.
Severe pemphigus vulgaris showing widespread flaccid blisters and erosions on the trunk.

See this image and copyright information in PMC

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References

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1. Brenner S, Tur E, Shapiro J. et al Pemphigus vulgaris: environmental factors. Occupational, behavioral, medical, and qualitative food frequency questionnaire. Int J Dermatol 2001; 40:562–9.10.1046/j.1365-4362.2001.01266.x - DOI - PubMed
1. Aoki V, Millikan RC, Rivitti EA. et al. Environmental risk factors in endemic pemphigus foliaceus (fogo selvagem). J Investig Dermatol Symp Proc 2004; 9:34–40.10.1111/j.1087-0024.2004.00833.x - DOI - PubMed
1. Gazit E, Loewenthal R. The immuno-genetics of pemphigus vulgaris. Autoimmun Rev 2005; 4:16–20. - PubMed

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