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Review
. 2009 Aug;9(4):371-5.
doi: 10.7861/clinmedicine.9-4-371.

Pemphigus: a brief review

Richard W Groves  1
Affiliations
Review

Pemphigus: a brief review

Richard W Groves. Clin Med (Lond). 2009 Aug.
No abstract available

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Figures

Fig 1.
Fig 1.
Histopathology of pemphigus vulgaris. There is rounding up and separation of keratinocytes from each other, resulting in intra-epithelial blister formation.
Fig 2.
Fig 2.
Pemphigus vulgaris direct immunofluorescence shows deposition of IgG in the intercellular spaces between epidermal keratinocytes.
Fig 3.
Fig 3.
Severe pemphigus vulgaris showing widespread flaccid blisters and erosions on the trunk.
See this image and copyright information in PMC

References

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    1. Simon DG, Krutchkoff D, Kaslow RA, Zarbo R. Pemphigus in Hartford County, Connecticut, from 1972 to 1977. Arch Dermatol 1980; 116:1035–7. - PubMed
    1. Brenner S, Tur E, Shapiro J. et al Pemphigus vulgaris: environmental factors. Occupational, behavioral, medical, and qualitative food frequency questionnaire. Int J Dermatol 2001; 40:562–9. 10.1046/j.1365-4362.2001.01266.x - DOI - PubMed
    1. Aoki V, Millikan RC, Rivitti EA. et al. Environmental risk factors in endemic pemphigus foliaceus (fogo selvagem). J Investig Dermatol Symp Proc 2004; 9:34–40. 10.1111/j.1087-0024.2004.00833.x - DOI - PubMed
    1. Gazit E, Loewenthal R. The immuno-genetics of pemphigus vulgaris. Autoimmun Rev 2005; 4:16–20. - PubMed