Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2009 Oct;13(5):343-9.
doi: 10.1007/s11916-009-0056-3.

Biomarkers in fibromyalgia

Jacob N Ablin  1 , Dan Buskila, Daniel J Clauw
Affiliations
Review

Biomarkers in fibromyalgia

Jacob N Ablin et al. Curr Pain Headache Rep. 2009 Oct.

Abstract

Fibromyalgia is a common pain syndrome characterized by widespread pain, tenderness, and a number of other somatic symptoms and syndromes. Although there was original skepticism that any objective abnormalities would be identified in these individuals, at present there are many that have been reproducibly identified, and most point to dysregulation of central nervous system function as a key underlying pathogenic mechanism in this and related illnesses. This article reviews several objective abnormalities or measures that have been identified or used in fibromyalgia, and indicates which of these may be most promising to eventually use as biomarkers to follow the response to treatment or progress of disease over time.

PubMed Disclaimer

References

    1. J Psychosom Res. 2004 Oct;57(4):391-8 - PubMed
    1. J Rheumatol. 1993 Nov;20(11):1925-31 - PubMed
    1. Rheumatol Int. 2005 Jun;25(5):345-9 - PubMed
    1. Pain. 2005 Mar;114(1-2):295-302 - PubMed
    1. Neuroscience. 2008 Nov 19;157(2):446-52 - PubMed

LinkOut - more resources