PI3Kbeta goes to the head of its class
- PMID: 19729533
- DOI: 10.1182/blood-2009-06-228551
PI3Kbeta goes to the head of its class
Abstract
In this issue of Blood, Canobbio and colleagues report on the unique and redundant contributions of 2 isoforms of PI3K, PI3Kbeta and PI3Kgamma, to platelet activation by GPCRs and ITAM-coupled receptors.
Comment on
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Genetic evidence for a predominant role of PI3Kbeta catalytic activity in ITAM- and integrin-mediated signaling in platelets.Blood. 2009 Sep 3;114(10):2193-6. doi: 10.1182/blood-2009-03-208074. Epub 2009 Jun 10. Blood. 2009. PMID: 19515725
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