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Editorial
. 2009 Sep 15;8(18):2861-2.
doi: 10.4161/cc.8.18.9402. Epub 2009 Sep 30.

A new (and different) circadian pacemaker

Jennifer A Mohawk, Michael Menaker
Editorial

A new (and different) circadian pacemaker

Jennifer A Mohawk et al. Cell Cycle. .
No abstract available

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Figures

Figure I
Figure I
Double plotted actogram from a mouse held in constant darkness. Consecutive days are plotted from left to right and top to bottom. Data are from running-wheel activity before, during, and after methamphetamine (MA) administration (0.01% supplied ad libitum in the drinking water). The period of MA administration is denoted on the left side of the actogram. Prior to MA the mouse displays a free-running circadian period slightly shorter than 24 h (as evidenced by the leftward slope of the actogram). MA causes a lengthening of the free-running period and 2 components can be observed—one running with a very long period and a second with a period closer to 24 h. After MA is withdrawn the mouse returns to its previous circadian free-running pattern within a few cycles. Figure is adapted from 4.
See this image and copyright information in PMC

References

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    1. Mohawk JA, et al. Proc Natl Acad Sci USA. 2009;106:3519–24. - PMC - PubMed

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