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. 2009 Jul;4(7):993-6.

Chemical composition and antimicrobial activity of the essential oil of Anaphalis nubigena var. monocephala

Rajesh K Joshi  1 , Chitra Pande, Mohammad H K Mujawar, Sanjiva D Kholkute
Affiliations
  • PMID: 19731610

Chemical composition and antimicrobial activity of the essential oil of Anaphalis nubigena var. monocephala

Rajesh K Joshi et al. Nat Prod Commun. 2009 Jul.

Abstract

The essential oil composition of the aerial parts of Anaphalis nubigena DC. var. monocephala (DC.) C. B. Clarke collected from Pindari glacier at a height of 3300 m, was analyzed by using GC and GC/MS. Sixty components were identified, accounting for 95.9% of the total oil. The main constituents were alpha-guaiene (12.3%), gamma-muurolene (10.4%), gamma-cadinene (8.3%), alpha-muurolol (7.4%), alpha-gurjunene (6.0%) and alpha-bulnesene (5.8%). The oil was found to be rich in sesquiterpene hydrocarbons (60.1%). The oil was active against Escherichia coli (NCIM 2065) and Klebsiella pneumoniae (NCIM 2957), with MIC values of 125 microg/mL and 500 microg/mL, respectively.

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