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Comment
. 2009 Sep 8;16(3):173-4.
doi: 10.1016/j.ccr.2009.08.014.

The yin-yang of tumor-associated neutrophils

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The yin-yang of tumor-associated neutrophils

Alberto Mantovani. Cancer Cell. .
Free article

Abstract

Cancer-related inflammation is a key component of the tumor microenvironment. A report in this issue of Cancer Cell now indicates that tumor-associated neutrophils in lung cancer can polarize to either "N1" or "N2" phenotype that inhibits or promotes cancer development, respectively.

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