Review
doi: 10.1093/bfgp/elp027.
On the causes of outliers in Affymetrix GeneChip data
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- PMID: 19734302
- DOI: 10.1093/bfgp/elp027
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Review
On the causes of outliers in Affymetrix GeneChip data
Brief Funct Genomic Proteomic.
2009 May.
Abstract
We describe various types of outliers seen in Affymetrix GeneChip data. We have been able to utilise the data in the Gene Expression Omnibus to screen GeneChips across a range of scales, from single probes, to spatially adjacent fractions of arrays, to whole arrays, to whole experiments. In this review we describe a number of causes for why some reported intensities might be misleading on GeneChips.
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