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. 2009 Sep 4;138(5):834-6.
doi: 10.1016/j.cell.2009.08.018.

IKKepsilon: a bridge between obesity and inflammation

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IKKepsilon: a bridge between obesity and inflammation

Jerrold M Olefsky. Cell. .
Free article

Abstract

Obesity leads to tissue inflammation and insulin resistance, which are features of metabolic diseases such as type 2 diabetes. Chiang et al. (2009) now show that the IkappaB kinase IKKepsilon is an important link between obesity and inflammation and may be a new therapeutic target for treating obesity-related metabolic diseases.

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