IKKepsilon: a bridge between obesity and inflammation
- PMID: 19737512
- DOI: 10.1016/j.cell.2009.08.018
IKKepsilon: a bridge between obesity and inflammation
Abstract
Obesity leads to tissue inflammation and insulin resistance, which are features of metabolic diseases such as type 2 diabetes. Chiang et al. (2009) now show that the IkappaB kinase IKKepsilon is an important link between obesity and inflammation and may be a new therapeutic target for treating obesity-related metabolic diseases.
Comment on
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The protein kinase IKKepsilon regulates energy balance in obese mice.Cell. 2009 Sep 4;138(5):961-75. doi: 10.1016/j.cell.2009.06.046. Cell. 2009. PMID: 19737522 Free PMC article.
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