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Case Reports
. 2009 Jul;3(4):167-70.

5-Fluorouracil-induced cardiotoxicity during chemotherapy for adenocarcinoma of the small bowel

Affiliations
Case Reports

5-Fluorouracil-induced cardiotoxicity during chemotherapy for adenocarcinoma of the small bowel

Mohamed H Abou El Fadl et al. Gastrointest Cancer Res. 2009 Jul.
No abstract available

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Figures

Figure 1.
Figure 1.
High-grade adenocarcinoma (circled) arising in a background of tubulovillous adenoma with muscularis propria and lymphatic invasion. Notice the irregular glands lined by pseudostratified columnar cells with hyperchromatic nuclei.
Figure 2.
Figure 2.
ST segment and T wave changes in leads I, aVL, V1–V6
Figure 3.
Figure 3.
Changes resolved
Figure 4.
Figure 4.
ST segment elevations and T wave changes in leads I, aVL, V1–V6
Figure 5:
Figure 5:
Changes resolved
Figure 6.
Figure 6.
Left main coronary artery
Figure 7.
Figure 7.
Left main coronary artery
Figure 8.
Figure 8.
Left main coronary artery
Figure 9.
Figure 9.
Right main coronary artery
Figure 10.
Figure 10.
Right main coronary artery
Figure 11.
Figure 11.
Pharmacological (adenosine) stress test showing no ischemic ST changes. Patient had no arrhythmias or chest pain and a stable blood pressure during the procedure.
Figure 12.
Figure 12.
Myocardial perfusion scan. The images above are dynamic gated images that show no scarring and good wall motion. The calculated ejection fraction of the left ventricle was 76%.
Figure 13.
Figure 13.
Myocardial perfusion scan (stress images). The images above show minimal nonspecific inferolateral adenosine-induced ischemia, which resolved at rest.

References

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    1. de Forni M, Malet-Martino MC, Jaillais P, et al. Cardiotoxicity of high-dose continuous infusion fluorouracil: a prospective clinical study. J Clin Oncol. 1992;10:1795–1801. - PubMed
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