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Clinical Trial
. 1990:38 Suppl 2:S167-70.
doi: 10.1007/BF01409490.

Blood-pressure-lowering effect of carvedilol vs nitrendipine in geriatric hypertensives

B Krönig  1 , L Widmann, C Staiger, M Machwirth, U Stienen, M Hennig, B Müller-Beckmann
Affiliations
Clinical Trial

Blood-pressure-lowering effect of carvedilol vs nitrendipine in geriatric hypertensives

B Krönig et al. Eur J Clin Pharmacol. 1990.

Abstract

Carvedilol and nitrendipine were given for 12 weeks in a double-blind study to 81 elderly patients (greater than or equal to 60 years) with essential hypertension. The effects on blood pressure were measured (Riva Rocci) before medication and after 2 h with the patient in a lying and standing position after 4 weeks of placebo therapy as well as after 4, 8 and 12 weeks of treatment. Carvedilol (25 mg/o.d.) reduced blood pressure measured in the supine and erect position very successfully, similar to the reduction achieved with nitrendipine (20 mg/o.d.), without influencing the pulse rate. Both substances were well tolerated. Carvedilol is an alternative substance for lowering high blood pressure in elderly hypertensive patients.

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References

    1. Lancet. 1983 Oct 29;2(8357):983-6 - PubMed
    1. Hypertension. 1985 May-Jun;7(3 Pt 1):457-68 - PubMed
    1. J Hypertens Suppl. 1988 Nov;6(1):S81-5 - PubMed
    1. J Cardiovasc Pharmacol. 1984;6 Suppl 7:S929-32 - PubMed
    1. Bull N Y Acad Med. 1978 Jun;54(6):573-91 - PubMed

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