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Clinical Trial
. 1990 Sep;147(9):1138-48.
doi: 10.1176/ajp.147.9.1138.

Continuous versus targeted medication in schizophrenic outpatients: outcome results

Affiliations
Clinical Trial

Continuous versus targeted medication in schizophrenic outpatients: outcome results

W T Carpenter Jr et al. Am J Psychiatry. 1990 Sep.

Erratum in

  • Am J Psychiatry 1991 Jun;148(6):819

Abstract

The authors report on the outcome of treatment of 116 outpatients with chronic schizophrenia who were assigned to a 2-year, single-blind course of treatment with either targeted or continuous medication. These patients were not restricted to those who were good candidates for a medication reduction strategy. Continuous medication was superior to targeted medication in preventing decompensations and hospitalizations and in extent of employment at 2 years. Other measures of psychopathology and functioning at 1 and 2 years did not differentiate the two groups of patients. The targeted approach achieved a substantial reduction in total medication through a reduction in the number of days of medication administration.

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Comment in

  • Targeted neuroleptic medication.
    Grey P. Grey P. Am J Psychiatry. 1991 Nov;148(11):1612-3. doi: 10.1176/ajp.148.11.aj148111612. Am J Psychiatry. 1991. PMID: 1681753 No abstract available.

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