Shifting the paradigm: host gene signatures for diagnosis of infectious diseases
- PMID: 19748461
- DOI: 10.1016/j.chom.2009.08.007
Shifting the paradigm: host gene signatures for diagnosis of infectious diseases
Abstract
Instead of focusing on the pathogen, in a paradigm shift, Zaas et al. (2009) identified host gene profiles as a strategy for diagnosis of respiratory infections. Application of host gene profiles offers tremendous possibilities for identification of diagnostic signatures, markers of disease severity, and eventually, prognostic indicators in the clinical setting.
Comment on
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Gene expression signatures diagnose influenza and other symptomatic respiratory viral infections in humans.Cell Host Microbe. 2009 Sep 17;6(3):207-17. doi: 10.1016/j.chom.2009.07.006. Epub 2009 Aug 6. Cell Host Microbe. 2009. PMID: 19664979 Free PMC article.
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