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Comment
. 2009 Sep 17;6(3):201-3.
doi: 10.1016/j.chom.2009.08.008.

A vitamin for autophagy

Mario Fabri  1 , Robert L Modlin
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Free article
Comment

A vitamin for autophagy

Mario Fabri et al. Cell Host Microbe. .
Free article

Abstract

Recent discoveries have revealed the importance of the vitamin D-dependent generation of antimicrobial peptides in human host defense against Mycobacterium tuberculosis. Now, Yuk et al. (2009) show how vitamin D induces autophagy and mediates colocalization of Mycobacterium tuberculosis and antimicrobial peptides within an autophagolysosome, leading to killing of the bacterium.

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