doi: 10.1093/nar/4.6.2057.
Escherichia coli DNA synthesis in vitro: insensitivity of ATP-dependent DNA repair to inhibition by novobiocin
- PMID: 197497
- PMCID: PMC342542
- DOI: 10.1093/nar/4.6.2057
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Escherichia coli DNA synthesis in vitro: insensitivity of ATP-dependent DNA repair to inhibition by novobiocin
Nucleic Acids Res.
1977 Jun.
Free PMC article
Abstract
Novobiocin, an effective inhibitor of DNA replicaion in Escherichia coli, is shown to have no effect on the ATP-dependent DNA repair carried out by toluenized cells after ultraviolet irradiation. Therefore novobiocin can be considered a selective inhibitor of replicative DNA synthesis in vitro.
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