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. 2009 Oct 15;11(20):4652-5.
doi: 10.1021/ol9019277.

Inter- and intramolecular addition reactions of electron-deficient alkenes with alkyl radicals, generated by SET-photochemical decarboxylation of carboxylic acids, serve as a mild and efficient method for the preparation of gamma-amino acids and macrocyclic lactones

Yasuharu Yoshimi  1 , Miho Masuda, Tomoyuki Mizunashi, Keisuke Nishikawa, Kousuke Maeda, Nobumasa Koshida, Tatsuya Itou, Toshio Morita, Minoru Hatanaka
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Inter- and intramolecular addition reactions of electron-deficient alkenes with alkyl radicals, generated by SET-photochemical decarboxylation of carboxylic acids, serve as a mild and efficient method for the preparation of gamma-amino acids and macrocyclic lactones

Yasuharu Yoshimi et al. Org Lett. .

Abstract

Inter- and intramolecular additions of alkyl radicals, generated by SET photochemical decarboxylation reactions of free carboxylic acids, to electron-deficient alkenes take place under mild conditions as part of efficient routes for the formation of N-Boc gamma-amino acids and macrocyclic lactones.

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