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Multicenter Study
. 2010 Jan;54(1):560-2.
doi: 10.1128/AAC.00762-09. Epub 2009 Sep 14.

Nonclonal emergence of colistin-resistant Klebsiella pneumoniae isolates from blood samples in South Korea

Ji-Yoeun Suh  1 , Jun Seong Son, Doo Ryeon Chung, Kyong Ran Peck, Kwan Soo Ko, Jae-Hoon Song
Affiliations
Multicenter Study

Nonclonal emergence of colistin-resistant Klebsiella pneumoniae isolates from blood samples in South Korea

Ji-Yoeun Suh et al. Antimicrob Agents Chemother. 2010 Jan.

Abstract

In vitro activities of colistin and other drugs were tested against 221 Klebsiella pneumoniae isolates that were collected between 2006 and 2007 in nine tertiary care South Korean hospitals from patients with bacteremia. The clonality of colistin-resistant K. pneumoniae (CRKP) isolates was assessed by multilocus sequence typing (MLST). We found that 15 isolates (6.8%) were resistant to colistin. MLST showed that CRKP isolates were nonclonal, with colistin resistance in K. pneumoniae occurring independently and not by clonal spreading.

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References

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