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. 1977 Jul;74(7):3052-5.
doi: 10.1073/pnas.74.7.3052.

Isolation and characterization of the opioid peptides from rat pituitary: beta-lipotropin

M Rubinstein, S Stein, L D Gerber, S Udenfriend

Isolation and characterization of the opioid peptides from rat pituitary: beta-lipotropin

M Rubinstein et al. Proc Natl Acad Sci U S A. 1977 Jul.

Abstract

Rat beta-lipotropin was isolated from 40 anterior pituitaries using high efficiency chromatography columns and sensitive fluorometric methods. The beta-lipotropin was characterized as to molecular weight, amino acid composition, and generation of opioid activity by trypsinization. Other opioid peptides, as well as a precursor to opioid peptides with a molecular weight larger than that of beta-lipotropin, were observed in this tissue.

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References

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