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Case Reports
. 2009 Nov;47(11):3763-4.
doi: 10.1128/JCM.00206-09. Epub 2009 Sep 16.

Clinical and resistance consequences of misquantification of plasma and cerebrospinal fluid human immunodeficiency virus type 1 (HIV-1) RNA in samples from an HIV-1 subtype G-infected patient

Constance Delaugerre  1 , Blandine Denis, Gilles Peytavin, Pierre Palmer, Thomas Mourez, Jerôme Le Goff, Jean-Michel Molina, François Simon
Affiliations
Case Reports

Clinical and resistance consequences of misquantification of plasma and cerebrospinal fluid human immunodeficiency virus type 1 (HIV-1) RNA in samples from an HIV-1 subtype G-infected patient

Constance Delaugerre et al. J Clin Microbiol. 2009 Nov.

Abstract

Human immunodeficiency virus (HIV) load is the main marker used to monitor antiviral treatment efficacy and resistance. We report a case of underquantification of HIV type 1 (HIV-1) RNA in plasma and cerebrospinal fluid from an HIV-1 subtype G-infected woman, leading to delayed diagnosis of HIV encephalitis and to the emergence of drug resistance.

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